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bp0005rdr13 | Pre-natal Programming of Lifetime Productivity and Health | REDR2002

Consequences of manipulating gametes and embryos of ruminant species

McEvoy TG , Ashworth CJ , Rooke JA , Sinclair KD

During the past 12 years, ruminants have provided a focus for some significant advances in mammalian reproductive biotechnologies. Lambs were the first offspring generated after nuclear transfer of fetal or adult cells to enucleated oocytes, and many calves of pre-determined gender are today the result of commercialized semen sexing. In 1990, the birth of one calf provided living proof that even 'dead' spermatozoa can be paternal, whereas, more recently, a short-lived ...